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However, traditional chromatographic purification, while effective, presents significant challenges at scale: High solvent consumption affecting operational costs Limited scalability impacting production capacity Complex handling of modified peptides affecting throughput Substantial infrastructure requirements driving capital expenses A Novel Solution The study introduces an innovative orthogonal purification technology called PurePep Easy Clean (PEC), demonstrating its application in liraglutide production

Minghua Liu: nothing to disclose

10 The American College of Cardiology/American Heart Association primary prevention of cardiovascular disease guideline supports the use of GLP-1 RAs in patients with T2D and high atherosclerotic CVD risk, but does not mention existing HF

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